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Mutants of complement component C3 cleaved by the C4-specific C1-s protease.

To identify some of the structural features determining specific protease recognition of complement components C3 and C4, we used site-specific mutagenesis to construct mutants of murine C3 that are cleaved by the C4-specific C1-s protease. Insertion of three amino acid residues corresponding to res...

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Bibliografiske detaljer
Main Authors: Mathias, P, Carrillo, C J, Zepf, N E, Cooper, N R, Ogata, R T
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49869/
https://ncbi.nlm.nih.gov/pubmed/1518837
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