Hepatitis C Virus NS3/4A Protease Inhibits Complement Activation by Cleaving Complement Component 4

BACKGROUND: It has been hypothesized that persistent hepatitis C virus (HCV) infection is mediated in part by viral proteins that abrogate the host immune response, including the complement system, but the precise mechanisms are not well understood. We investigated whether HCV proteins are involved...

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Detalhes bibliográficos
Main Authors: Mawatari, Seiichi, Uto, Hirofumi, Ido, Akio, Nakashima, Kenji, Suzuki, Tetsuro, Kanmura, Shuji, Kumagai, Kotaro, Oda, Kohei, Tabu, Kazuaki, Tamai, Tsutomu, Moriuchi, Akihiro, Oketani, Makoto, Shimada, Yuko, Sudoh, Masayuki, Shoji, Ikuo, Tsubouchi, Hirohito
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861371/
https://ncbi.nlm.nih.gov/pubmed/24349192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082094
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