Human neutrophil peptide-1 promotes alcohol-induced hepatic fibrosis and hepatocyte apoptosis

BACKGROUND AND AIMS: Neutrophil infiltration of the liver is a typical feature of alcoholic liver injury. Human neutrophil peptide (HNP)-1 is an antimicrobial peptide secreted by neutrophils. The aim of this study was to determine if HNP-1 affects ethanol-induced liver injury and to examine the mech...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ibusuki, Rie, Uto, Hirofumi, Oda, Kohei, Ohshige, Akihiko, Tabu, Kazuaki, Mawatari, Seiichi, Kumagai, Kotaro, Kanmura, Shuji, Tamai, Tsutomu, Moriuchi, Akihiro, Tsubouchi, Hirohito, Ido, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389644/
https://ncbi.nlm.nih.gov/pubmed/28403148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174913
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