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Mutants of complement component C3 cleaved by the C4-specific C1-s protease.

To identify some of the structural features determining specific protease recognition of complement components C3 and C4, we used site-specific mutagenesis to construct mutants of murine C3 that are cleaved by the C4-specific C1-s protease. Insertion of three amino acid residues corresponding to res...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Mathias, P, Carrillo, C J, Zepf, N E, Cooper, N R, Ogata, R T
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1992
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49869/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1518837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.17.8125
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