The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion

Stress adaptation plays a pivotal role in biological processes and requires tight regulation of gene expression. In this study, we explored the effect of cellular stress on mRNA polyadenylation and investigated the implications of regulated polyadenylation site usage on mammalian gene expression. Hi...

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Gepubliceerd in:RNA
Hoofdauteurs: Hollerer, Ina, Curk, Tomaz, Haase, Bettina, Benes, Vladimir, Hauer, Christian, Neu-Yilik, Gabriele, Bhuvanagiri, Madhuri, Hentze, Matthias W., Kulozik, Andreas E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986898/
https://ncbi.nlm.nih.gov/pubmed/27407180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055657.115
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