Integrin α5β1 and p53 convergent pathways in the control of anti-apoptotic proteins PEA-15 and survivin in high-grade glioma

Integrin α5β1 expression is correlated with a worse prognosis in high-grade glioma. We previously unraveled a negative crosstalk between integrin α5β1 and p53 pathway, which was proposed to be part of the resistance of glioblastoma to chemotherapies. The restoration of p53 tumor-suppressor function...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Differ
Asıl Yazarlar: Renner, G, Janouskova, H, Noulet, F, Koenig, V, Guerin, E, Bär, S, Nuesch, J, Rechenmacher, F, Neubauer, S, Kessler, H, Blandin, A-F, Choulier, L, Etienne-Selloum, N, Lehmann, M, Lelong-Rebel, I, Martin, S, Dontenwill, M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986636/
https://ncbi.nlm.nih.gov/pubmed/26470725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.131
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