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Rapamycin induces the anti-apoptotic protein survivin in neuroblastoma

Neuroblastoma is the most common solid tumor of infancy, accounting for 15% of all cancer cell deaths in children. Expression of the anti-apoptotic protein survivin in these tumors correlates with poor prognostic features and resistance to therapy. The mammalian target of rapamycin (mTOR) protein is...

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Hlavní autoři: Samkari, Ayman, Cooper, Zachary A, Holloway, Michael P, Liu, Jiebin, Altura, Rachel A
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325774/
https://ncbi.nlm.nih.gov/pubmed/22509478
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