Acetylation Directs Survivin Nuclear Localization to Repress STAT3 Oncogenic Activity

The multiple functions of the oncofetal protein survivin are dependent on its selective expression patterns within immunochemically distinct subcellular pools. The mechanism by which survivin localizes to these compartments, however, is only partly understood. Here we show that nuclear accumulation...

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Bibliografiske detaljer
Main Authors: Wang, Haijuan, Holloway, Michael P., Ma, Li, Cooper, Zachary A., Riolo, Matthew, Samkari, Ayman, Elenitoba-Johnson, Kojo S. J., Chin, Y. Eugene, Altura, Rachel A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975235/
https://ncbi.nlm.nih.gov/pubmed/20826784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.152777
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