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Injured astrocytes are repaired by Synaptotagmin XI-regulated lysosome exocytosis

Astrocytes are known to facilitate repair following brain injury; however, little is known about how injured astrocytes repair themselves. Repair of cell membrane injury requires Ca(2+)-triggered vesicle exocytosis. In astrocytes, lysosomes are the main Ca(2+)-regulated exocytic vesicles. Here we sh...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Principais autores: Sreetama, S C, Takano, T, Nedergaard, M, Simon, S M, Jaiswal, J K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986631/
https://ncbi.nlm.nih.gov/pubmed/26450452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.124
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