Synaptotagmin VII Restricts Fusion Pore Expansion during Lysosomal Exocytosis

Synaptotagmin is considered a calcium-dependent trigger for regulated exocytosis. We examined the role of synaptotagmin VII (Syt VII) in the calcium-dependent exocytosis of individual lysosomes in wild-type (WT) and Syt VII knockout (KO) mouse embryonic fibroblasts (MEFs) using total internal reflec...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Jaiswal, Jyoti K, Chakrabarti, Sabyasachi, Andrews, Norma W, Simon, Sanford M
Formato: Artigo
Idioma:Inglês
Publicado em: PLOS 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC439782/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15226824/
https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0020233
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