Siglec-H protects from virus-triggered severe systemic autoimmunity

It is controversial whether virus infections can contribute to the development of autoimmune diseases. Type I interferons (IFNs) are critical antiviral cytokines during virus infections and have also been implicated in the pathogenesis of systemic lupus erythematosus. Type I IFN is mainly produced b...

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Publicat a:J Exp Med
Autors principals: Schmitt, Heike, Sell, Sabrina, Koch, Julia, Seefried, Martina, Sonnewald, Sophia, Daniel, Christoph, Winkler, Thomas H., Nitschke, Lars
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986536/
https://ncbi.nlm.nih.gov/pubmed/27377589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160189
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