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TNF activation of NF-κB is essential for development of single-positive thymocytes

NF-κB activation has been implicated at multiple stages of thymic development of T cells, during which it is thought to mediate developmental signals originating from the T cell receptor (TCR). However, the Card11–Bcl10–Malt1 (CBM) complex that is essential for TCR activation of NF-κB in peripheral...

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Bibliographic Details
Published in:J Exp Med
Main Authors: Webb, Louise V., Ley, Steven C., Seddon, Benedict
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986527/
https://ncbi.nlm.nih.gov/pubmed/27432943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151604
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