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Micro–adhesion rings surrounding TCR microclusters are essential for T cell activation
The immunological synapse (IS) formed at the interface between T cells and antigen-presenting cells represents a hallmark of initiation of acquired immunity. T cell activation is initiated at T cell receptor (TCR) microclusters (MCs), in which TCRs and signaling molecules assemble at the interface b...
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| Publié dans: | J Exp Med |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4986522/ https://ncbi.nlm.nih.gov/pubmed/27354546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151088 |
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