Micro–adhesion rings surrounding TCR microclusters are essential for T cell activation

The immunological synapse (IS) formed at the interface between T cells and antigen-presenting cells represents a hallmark of initiation of acquired immunity. T cell activation is initiated at T cell receptor (TCR) microclusters (MCs), in which TCRs and signaling molecules assemble at the interface b...

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Publicado en:J Exp Med
Autores principales: Hashimoto-Tane, Akiko, Sakuma, Machie, Ike, Hiroshi, Yokosuka, Tadashi, Kimura, Yayoi, Ohara, Osamu, Saito, Takashi
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986522/
https://ncbi.nlm.nih.gov/pubmed/27354546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151088
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