The deficiency of galectin-3 in stromal cells leads to enhanced tumor growth and bone marrow metastasis

BACKGROUND: Galectin-3 is a multifunctional β-galactoside-binding lectin that once synthesized, is expressed in the nucleus, cytoplasm, cell surface and in the extracellular environment. Because of its unique structure, galectin-3 can oligomerize forming lattice upon binding to multivalent oligossac...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Pereira, Jonathas Xavier, Azeredo, Maria Carolina Braga, Martins, Felipe Sá, Chammas, Roger, Oliveira, Felipe Leite, Santos, Sofia Nascimento, Bernardes, Emerson Soares, El-Cheikh, Márcia Cury
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986277/
https://ncbi.nlm.nih.gov/pubmed/27526676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2679-1
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