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The deficiency of galectin-3 in stromal cells leads to enhanced tumor growth and bone marrow metastasis

BACKGROUND: Galectin-3 is a multifunctional β-galactoside-binding lectin that once synthesized, is expressed in the nucleus, cytoplasm, cell surface and in the extracellular environment. Because of its unique structure, galectin-3 can oligomerize forming lattice upon binding to multivalent oligossac...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Pereira, Jonathas Xavier, Azeredo, Maria Carolina Braga, Martins, Felipe Sá, Chammas, Roger, Oliveira, Felipe Leite, Santos, Sofia Nascimento, Bernardes, Emerson Soares, El-Cheikh, Márcia Cury
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986277/
https://ncbi.nlm.nih.gov/pubmed/27526676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2679-1
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