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Phosphatase Rtr1 Regulates Global Levels of Serine 5 RNA Polymerase II C-Terminal Domain Phosphorylation and Cotranscriptional Histone Methylation

In eukaryotes, the C-terminal domain (CTD) of Rpb1 contains a heptapeptide repeat sequence of (Y(1)S(2)P(3)T(4)S(5)P(6)S(7))(n) that undergoes reversible phosphorylation through the opposing action of kinases and phosphatases. Rtr1 is a conserved protein that colocalizes with RNA polymerase II (RNAP...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Hunter, Gerald O., Fox, Melanie J., Smith-Kinnaman, Whitney R., Gogol, Madelaine, Fleharty, Brian, Mosley, Amber L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985930/
https://ncbi.nlm.nih.gov/pubmed/27247267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00870-15
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