Histone Deacetylases and Phosphorylated Polymerase II C-Terminal Domain Recruit Spt6 for Cotranscriptional Histone Reassembly

Spt6 is a multifunctional histone chaperone involved in the maintenance of chromatin structure during elongation by RNA polymerase II (Pol II). Spt6 has a tandem SH2 (tSH2) domain within its C terminus that recognizes Pol II C-terminal domain (CTD) peptides phosphorylated on Ser2, Ser5, or Try1 in v...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Burugula, Bala Bharathi, Jeronimo, Célia, Pathak, Rakesh, Jones, Jeffery W., Robert, François, Govind, Chhabi K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248711/
https://ncbi.nlm.nih.gov/pubmed/25182531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00695-14
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