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Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD

The phosphorylation state of heptapeptide repeats within the C-terminal domain (CTD) of the largest subunit of RNA Polymerase II (PolII) controls the transcription cycle and is maintained by the competing action of kinases and phosphatases. Rtr1 was recently proposed to be the enzyme responsible for...

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Bibliografiske detaljer
Main Authors: Hsu, Peter L., Yang, Fan, Smith-Kinnaman, Whitney, Yang, Wen, Song, Jae-Eun, Mosley, Amber L., Varani, Gabriele
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119023/
https://ncbi.nlm.nih.gov/pubmed/24951832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.06.010
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