Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD

The phosphorylation state of heptapeptide repeats within the C-terminal domain (CTD) of the largest subunit of RNA Polymerase II (PolII) controls the transcription cycle and is maintained by the competing action of kinases and phosphatases. Rtr1 was recently proposed to be the enzyme responsible for...

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Bibliographic Details
Main Authors: Hsu, Peter L., Yang, Fan, Smith-Kinnaman, Whitney, Yang, Wen, Song, Jae-Eun, Mosley, Amber L., Varani, Gabriele
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119023/
https://ncbi.nlm.nih.gov/pubmed/24951832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.06.010
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