Proteomic differences in recombinant CHO cells producing two similar antibody fragments

Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for the production of biopharmaceuticals. To overcome unfavorable features of CHO cells, a lot of effort is put into cell engineering to improve phenotype. “Omics” studies investigating elevated growth rate and specific pro...

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Bibliografiske detaljer
Udgivet i:Biotechnol Bioeng
Main Authors: Sommeregger, Wolfgang, Mayrhofer, Patrick, Steinfellner, Willibald, Reinhart, David, Henry, Michael, Clynes, Martin, Meleady, Paula, Kunert, Renate
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985663/
https://ncbi.nlm.nih.gov/pubmed/26913574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25957
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