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Proteomic differences in recombinant CHO cells producing two similar antibody fragments

Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for the production of biopharmaceuticals. To overcome unfavorable features of CHO cells, a lot of effort is put into cell engineering to improve phenotype. “Omics” studies investigating elevated growth rate and specific pro...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Sommeregger, Wolfgang, Mayrhofer, Patrick, Steinfellner, Willibald, Reinhart, David, Henry, Michael, Clynes, Martin, Meleady, Paula, Kunert, Renate
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985663/
https://ncbi.nlm.nih.gov/pubmed/26913574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25957
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