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Proteomic differences in recombinant CHO cells producing two similar antibody fragments

Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for the production of biopharmaceuticals. To overcome unfavorable features of CHO cells, a lot of effort is put into cell engineering to improve phenotype. “Omics” studies investigating elevated growth rate and specific pro...

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Dettagli Bibliografici
Pubblicato in:Biotechnol Bioeng
Autori principali: Sommeregger, Wolfgang, Mayrhofer, Patrick, Steinfellner, Willibald, Reinhart, David, Henry, Michael, Clynes, Martin, Meleady, Paula, Kunert, Renate
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985663/
https://ncbi.nlm.nih.gov/pubmed/26913574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25957
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