Identification of inhibitors of the transmembrane protease FlaK of Methanococcus maripaludis

GxGD‐type intramembrane cleaving proteases (I‐CLiPs) form a family of proteolytic enzymes that feature an aspartate‐based catalytic mechanism. Yet, they structurally and functionally largely differ from the classical pepsin‐like aspartic proteases. Among them are the archaeal enzyme FlaK, processing...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Microbiologyopen
Egile Nagusiak: Coburger, Ina, Schaub, Yvonne, Roeser, Dirk, Hardes, Kornelia, Maeder, Patrick, Klee, Nina, Steinmetzer, Torsten, Imhof, Diana, Diederich, Wibke E., Than, Manuel E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985597/
https://ncbi.nlm.nih.gov/pubmed/27038342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.358
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