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Identification of inhibitors of the transmembrane protease FlaK of Methanococcus maripaludis

GxGD‐type intramembrane cleaving proteases (I‐CLiPs) form a family of proteolytic enzymes that feature an aspartate‐based catalytic mechanism. Yet, they structurally and functionally largely differ from the classical pepsin‐like aspartic proteases. Among them are the archaeal enzyme FlaK, processing...

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Detaylı Bibliyografya
Yayımlandı:Microbiologyopen
Asıl Yazarlar: Coburger, Ina, Schaub, Yvonne, Roeser, Dirk, Hardes, Kornelia, Maeder, Patrick, Klee, Nina, Steinmetzer, Torsten, Imhof, Diana, Diederich, Wibke E., Than, Manuel E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985597/
https://ncbi.nlm.nih.gov/pubmed/27038342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.358
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