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Identification of inhibitors of the transmembrane protease FlaK of Methanococcus maripaludis
GxGD‐type intramembrane cleaving proteases (I‐CLiPs) form a family of proteolytic enzymes that feature an aspartate‐based catalytic mechanism. Yet, they structurally and functionally largely differ from the classical pepsin‐like aspartic proteases. Among them are the archaeal enzyme FlaK, processing...
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| Pubblicato in: | Microbiologyopen |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4985597/ https://ncbi.nlm.nih.gov/pubmed/27038342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.358 |
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