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A Quality by Experimental Design Approach to Assess the Effect of Formulation and Process Variables on the Extrusion and Spheronization of Drug-Loaded Pellets Containing Polyplasdone(®) XL-10

Successful pellet production has been reported in literature with cross-linked poly(vinylpyrrolidone), Polyplasdone(®) XL-10 and INF-10. In the present study, a quality by experimental design approach was used to assess several formulation and process parameter effects on the characteristics of Poly...

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Bibliographische Detailangaben
Veröffentlicht in:AAPS PharmSciTech
Hauptverfasser: Saripella, Kalyan K., Loka, Nikhil C., Mallipeddi, Rama, Rane, Anuja M., Neau, Steven H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984875/
https://ncbi.nlm.nih.gov/pubmed/26169900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0345-6
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