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A Quality by Experimental Design Approach to Assess the Effect of Formulation and Process Variables on the Extrusion and Spheronization of Drug-Loaded Pellets Containing Polyplasdone(®) XL-10
Successful pellet production has been reported in literature with cross-linked poly(vinylpyrrolidone), Polyplasdone(®) XL-10 and INF-10. In the present study, a quality by experimental design approach was used to assess several formulation and process parameter effects on the characteristics of Poly...
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| Udgivet i: | AAPS PharmSciTech |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4984875/ https://ncbi.nlm.nih.gov/pubmed/26169900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0345-6 |
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