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Tn10 insertion specificity is strongly dependent upon sequences immediately adjacent to the target-site consensus sequence.

Transposon Tn10 inserts preferentially into particular "hotspots" that have been shown by sequence analysis to contain the symmetrical consensus sequence 5'-GCTNAGC-3'. This consensus is necessary but not sufficient to determine insertion specificity. We have mutagenized a known...

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Bibliografske podrobnosti
Main Authors: Bender, J, Kleckner, N
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC49842/
https://ncbi.nlm.nih.gov/pubmed/1325639
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