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Tn10 insertion specificity is strongly dependent upon sequences immediately adjacent to the target-site consensus sequence.

Transposon Tn10 inserts preferentially into particular "hotspots" that have been shown by sequence analysis to contain the symmetrical consensus sequence 5'-GCTNAGC-3'. This consensus is necessary but not sufficient to determine insertion specificity. We have mutagenized a known hotspot to identify...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Bender, J, Kleckner, N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1992
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49842/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1325639/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.17.7996
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