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Sumoylation of FOXP2 regulates motor function and vocal communication through Purkinje cell development

BACKGROUND: Mutations in the gene encoding the transcription factor forkhead box P2, FOXP2, result in brain developmental abnormalities including reduced gray matter in both human patients and rodent models, and speech and language deficits. However, neither the region-specific function of FOXP2 in...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Usui, Noriyoshi, Co, Marissa, Harper, Matthew, Rieger, Michael A., Dougherty, Joseph D., Konopka, Genevieve
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983264/
https://ncbi.nlm.nih.gov/pubmed/27009683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.02.008
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