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Sumoylation of FOXP2 regulates motor function and vocal communication through Purkinje cell development

BACKGROUND: Mutations in the gene encoding the transcription factor forkhead box P2, FOXP2, result in brain developmental abnormalities including reduced gray matter in both human patients and rodent models, and speech and language deficits. However, neither the region-specific function of FOXP2 in...

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Detalles Bibliográficos
Publicado en:Biol Psychiatry
Autores principales: Usui, Noriyoshi, Co, Marissa, Harper, Matthew, Rieger, Michael A., Dougherty, Joseph D., Konopka, Genevieve
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983264/
https://ncbi.nlm.nih.gov/pubmed/27009683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.02.008
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