Sumoylation of FOXP2 regulates motor function and vocal communication through Purkinje cell development

BACKGROUND: Mutations in the gene encoding the transcription factor forkhead box P2, FOXP2, result in brain developmental abnormalities including reduced gray matter in both human patients and rodent models, and speech and language deficits. However, neither the region-specific function of FOXP2 in...

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Bibliografiske detaljer
Udgivet i:Biol Psychiatry
Main Authors: Usui, Noriyoshi, Co, Marissa, Harper, Matthew, Rieger, Michael A., Dougherty, Joseph D., Konopka, Genevieve
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983264/
https://ncbi.nlm.nih.gov/pubmed/27009683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.02.008
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