Integrin-Associated Focal Adhesion Kinase Protects Human Embryonic Stem Cells from Apoptosis, Detachment, and Differentiation

Human embryonic stem cells (hESCs) can be maintained in a fully defined niche on extracellular matrix substrates, to which they attach through integrin receptors. However, the underlying integrin signaling mechanisms, and their contribution to hESC behavior, are largely unknown. Here, we show that f...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Vitillo, Loriana, Baxter, Melissa, Iskender, Banu, Whiting, Paul, Kimber, Susan J.
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983079/
https://ncbi.nlm.nih.gov/pubmed/27509133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.07.006
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