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Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis.

Focal adhesion kinase (FAK) has a central role in adhesion-mediated cell signalling. The N-terminus of FAK is thought to function as a docking site for a number of proteins, including the Src-family tyrosine kinases. In the present study, we disrupted FAK signalling by expressing the N-terminal doma...

詳細記述

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書誌詳細
主要な著者: Beviglia, Lucia, Golubovskaya, Vita, Xu, LiHui, Yang, XiHui, Craven, Rolf J, Cance, William G
フォーマット: Artigo
言語:Inglês
出版事項: 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223465/
https://ncbi.nlm.nih.gov/pubmed/12659633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021846
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