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Inhibition of Focal Adhesion Kinase and Src Increases Detachment and Apoptosis in Human Neuroblastoma Cell Lines

Neuroblastoma is the most common extracranial solid tumor of childhood. Focal adhesion kinase (FAK) is an intracellular kinase that is overexpressed in a number of human tumors including neuroblastoma, and regulates both cellular adhesion and survival. We have studied the effects of FAK inhibition u...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Beierle, Elizabeth A., Ma, Xiaojie, Trujillo, Angelica, Kurenova, Elena V., Cance, William G., Golubovskaya, Vita M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849163/
https://ncbi.nlm.nih.gov/pubmed/19885861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20592
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