Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency

Induced pluripotent stem cells (iPSCs) represent an innovative source for the standardized in vitro generation of macrophages (Mφ). We here describe a robust and efficient protocol to obtain mature and functional Mφ from healthy as well as disease-specific murine iPSCs. With regard to morphology, su...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cell Reports
Prif Awduron: Mucci, Adele, Kunkiel, Jessica, Suzuki, Takuji, Brennig, Sebastian, Glage, Silke, Kühnel, Mark P., Ackermann, Mania, Happle, Christine, Kuhn, Alexandra, Schambach, Axel, Trapnell, Bruce C., Hansen, Gesine, Moritz, Thomas, Lachmann, Nico
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2016
Pynciau:
Resource
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982988/
https://ncbi.nlm.nih.gov/pubmed/27453007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.06.011
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