Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency

Induced pluripotent stem cells (iPSCs) represent an innovative source for the standardized in vitro generation of macrophages (Mφ). We here describe a robust and efficient protocol to obtain mature and functional Mφ from healthy as well as disease-specific murine iPSCs. With regard to morphology, su...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cell Reports
Auteurs principaux: Mucci, Adele, Kunkiel, Jessica, Suzuki, Takuji, Brennig, Sebastian, Glage, Silke, Kühnel, Mark P., Ackermann, Mania, Happle, Christine, Kuhn, Alexandra, Schambach, Axel, Trapnell, Bruce C., Hansen, Gesine, Moritz, Thomas, Lachmann, Nico
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016
Sujets:
Resource
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982988/
https://ncbi.nlm.nih.gov/pubmed/27453007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.06.011
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires