Inflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrene

Neutrophils infiltrate tissues during inflammation, and when activated, they release β-glucuronidase. Since inflammation is associated with carcinogenesis, we investigated how extracellular β-glucuronidase changed the in vitro cellular response to the chemical carcinogen benzo(a)pyrene (B[a]P). For...

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Vydáno v:Arch Toxicol
Hlavní autoři: Shi, Q., Haenen, G. R., Maas, L., Arlt, V. M., Spina, D., Vasquez, Y. Riffo, Moonen, E., Veith, C., Van Schooten, F. J., Godschalk, R. W. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2015
Témata:
Genotoxicity and Carcinogenicity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982897/
https://ncbi.nlm.nih.gov/pubmed/26438400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-015-1593-7
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