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Pan-Cancer Analysis of Mutation Hotspots in Protein Domains
In cancer genomics, recurrence of mutations in independent tumor samples is a strong indicator of functional impact. However, rare functional mutations can escape detection by recurrence analysis owing to lack of statistical power. We enhance statistical power by extending the notion of recurrence o...
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| Publicado no: | Cell Syst |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4982675/ https://ncbi.nlm.nih.gov/pubmed/27135912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2015.08.014 |
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