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Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations
We present a novel method for the identification of sets of mutually exclusive gene alterations in a given set of genomic profiles. We scan the groups of genes with a common downstream effect on the signaling network, using a mutual exclusivity criterion that ensures that each gene in the group sign...
Tallennettuna:
| Julkaisussa: | Genome Biol |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381444/ https://ncbi.nlm.nih.gov/pubmed/25887147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0612-6 |
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