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Prediction of individualized therapeutic vulnerabilities in cancer from genomic profiles
Motivation: Somatic homozygous deletions of chromosomal regions in cancer, while not necessarily oncogenic, may lead to therapeutic vulnerabilities specific to cancer cells compared with normal cells. A recently reported example is the loss of one of the two isoenzymes in glioblastoma cancer cells s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4080742/ https://ncbi.nlm.nih.gov/pubmed/24665131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu164 |
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