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Functional relevance of naturally occurring mutations in adhesion G protein-coupled receptor ADGRD1 (GPR133)

BACKGROUND: A large number of human inherited and acquired diseases and phenotypes are caused by mutations in G protein-coupled receptors (GPCR). Genome-wide association studies (GWAS) have shown that variations in the ADGRD1 (GPR133) locus are linked with differences in metabolism, human height and...

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Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Fischer, Liane, Wilde, Caroline, Schöneberg, Torsten, Liebscher, Ines
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982218/
https://ncbi.nlm.nih.gov/pubmed/27516204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2937-2
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