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A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-coupled Receptors GPR126 and GPR133
Adhesion G protein-coupled receptors (aGPCRs) comprise the second largest yet least studied class of the GPCR superfamily. aGPCRs are involved in many developmental processes, immune and synaptic functions, but the mode of their signal transduction is unclear. Here, we show that a short peptide sequ...
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Publicado no: | Cell Rep |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277498/ https://ncbi.nlm.nih.gov/pubmed/25533341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.11.036 |
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