A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-coupled Receptors GPR126 and GPR133

Adhesion G protein-coupled receptors (aGPCRs) comprise the second largest yet least studied class of the GPCR superfamily. aGPCRs are involved in many developmental processes, immune and synaptic functions, but the mode of their signal transduction is unclear. Here, we show that a short peptide sequ...

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Udgivet i:Cell Rep
Main Authors: Liebscher, Ines, Schön, Julia, Petersen, Sarah C., Fischer, Liane, Auerbach, Nina, Demberg, Lilian Marie, Mogha, Amit, Cöster, Maxi, Simon, Kay-Uwe, Rothemund, Sven, Monk, Kelly R., Schöneberg, Torsten
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277498/
https://ncbi.nlm.nih.gov/pubmed/25533341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.11.036
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