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A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-coupled Receptors GPR126 and GPR133

Adhesion G protein-coupled receptors (aGPCRs) comprise the second largest yet least studied class of the GPCR superfamily. aGPCRs are involved in many developmental processes, immune and synaptic functions, but the mode of their signal transduction is unclear. Here, we show that a short peptide sequ...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Liebscher, Ines, Schön, Julia, Petersen, Sarah C., Fischer, Liane, Auerbach, Nina, Demberg, Lilian Marie, Mogha, Amit, Cöster, Maxi, Simon, Kay-Uwe, Rothemund, Sven, Monk, Kelly R., Schöneberg, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277498/
https://ncbi.nlm.nih.gov/pubmed/25533341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.11.036
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