Development and validation of a turbulent flow chromatography and tandem mass spectrometry method for the quantitation of methotrexate and its metabolites 7-hydroxy methotrexate and DAMPA in serum

A rapid and simple turbulent flow liquid chromatography (TFC–LC) method implementing positive heated electrospray ionization (HESI) for the accurate and precise determination of methotrexate (MTX), 7-hydroxy methotrexate (7-OH MTX), and 4-amino-4-deoxy-N(10)-methylpteroic acid (DAMPA) concentrations...

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Detaylı Bibliyografya
Yayımlandı:J Chromatogr B Analyt Technol Biomed Life Sci
Asıl Yazarlar: Schofield, Ryan C., Ramanathan, Lakshmi V., Murata, Kazunori, Grace, Marie, Fleisher, Martin, Pessin, Melissa S., Carlow, Dean C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982141/
https://ncbi.nlm.nih.gov/pubmed/26322588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.08.025
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