Cryptic activity within the Type III(1) domain of fibronectin regulates tissue inflammation and angiogenesis

The fibronectin matrix provides mechanical and biochemical information to regulate homeostatic and pathological processes within tissues. Fibronectin consists of independently-folded modules termed Types I, II and III. In response to cellular contractile force, Type III domains unfold to initiate a...

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Bibliographic Details
Published in:Curr Top Pept Protein Res
Main Authors: Cho, Christina, Kelsh-Lasher, Rhiannon, Ambesi, Anthony, McKeown-Longo, Paula J.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981920/
https://ncbi.nlm.nih.gov/pubmed/27524870
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