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Conformational remodeling of the fibronectin matrix selectively regulates VEGF signaling

The fibronectin matrix plays a crucial role in the regulation of angiogenesis during development, tissue repair and pathogenesis. Previous work has identified a fibronectin-derived homophilic binding peptide, anastellin, as an effective inhibitor of angiogenesis; however, its mechanism of action is...

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Autors principals: Ambesi, Anthony, McKeown-Longo, Paula J.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150064/
https://ncbi.nlm.nih.gov/pubmed/24982443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.150458
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