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ANASTELLIN, THE ANGIOSTATIC FIBRONECTIN PEPTIDE, IS A SELECTIVE INHIBITOR OF LYSOPHOSPHOLIPID SIGNALING

Angiogenesis is regulated by integrin-dependent cell adhesion and the activation of specific cell surface receptors on vascular endothelial cells by angiogenic factors. LPA and S1P are bioactive lysophospholipids which activate G-protein-coupled receptors that stimulate PI3-kinase, Ras, and Rho effe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ambesi, Anthony, McKeown-Longo, Paula J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658630/
https://ncbi.nlm.nih.gov/pubmed/19208746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0195
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