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ANASTELLIN, THE ANGIOSTATIC FIBRONECTIN PEPTIDE, IS A SELECTIVE INHIBITOR OF LYSOPHOSPHOLIPID SIGNALING
Angiogenesis is regulated by integrin-dependent cell adhesion and the activation of specific cell surface receptors on vascular endothelial cells by angiogenic factors. LPA and S1P are bioactive lysophospholipids which activate G-protein-coupled receptors that stimulate PI3-kinase, Ras, and Rho effe...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2658630/ https://ncbi.nlm.nih.gov/pubmed/19208746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0195 |
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