Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart Disease

AGGF1 is an angiogenic factor with therapeutic potential to treat coronary artery disease (CAD) and myocardial infarction (MI). However, the underlying mechanism for AGGF1-mediated therapeutic angiogenesis is unknown. Here, we show for the first time that AGGF1 activates autophagy, a housekeeping ca...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Lu, Qiulun, Yao, Yufeng, Hu, Zhenkun, Hu, Changqing, Song, Qixue, Ye, Jian, Xu, Chengqi, Wang, Annabel Z., Chen, Qiuyun, Wang, Qing Kenneth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981375/
https://ncbi.nlm.nih.gov/pubmed/27513923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002529
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