Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart Disease

AGGF1 is an angiogenic factor with therapeutic potential to treat coronary artery disease (CAD) and myocardial infarction (MI). However, the underlying mechanism for AGGF1-mediated therapeutic angiogenesis is unknown. Here, we show for the first time that AGGF1 activates autophagy, a housekeeping ca...

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Pubblicato in:PLoS Biol
Autori principali: Lu, Qiulun, Yao, Yufeng, Hu, Zhenkun, Hu, Changqing, Song, Qixue, Ye, Jian, Xu, Chengqi, Wang, Annabel Z., Chen, Qiuyun, Wang, Qing Kenneth
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981375/
https://ncbi.nlm.nih.gov/pubmed/27513923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002529
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