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Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart Disease

AGGF1 is an angiogenic factor with therapeutic potential to treat coronary artery disease (CAD) and myocardial infarction (MI). However, the underlying mechanism for AGGF1-mediated therapeutic angiogenesis is unknown. Here, we show for the first time that AGGF1 activates autophagy, a housekeeping ca...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Lu, Qiulun, Yao, Yufeng, Hu, Zhenkun, Hu, Changqing, Song, Qixue, Ye, Jian, Xu, Chengqi, Wang, Annabel Z., Chen, Qiuyun, Wang, Qing Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981375/
https://ncbi.nlm.nih.gov/pubmed/27513923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002529
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