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Hydroxyl radical cleavage of tRNA in the ribosomal P site.

Hydroxyl radical is a useful probe of the accessibility of the sugar moiety of nucleic acids to solvent. Here we compare the accessibility of free and ribosome-bound yeast tRNA(Phe), Escherichia coli tRNA(Phe), and E. coli tRNA(Leu2) to attack by hydroxyl radicals generated from Fe(2+)-EDTA. When bo...

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Bibliografiska uppgifter
Huvudupphovsmän: Hüttenhofer, A, Noller, H F
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC49812/
https://ncbi.nlm.nih.gov/pubmed/1381501
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