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How the Ribosome Hands the A-site tRNA to the P Site During EF-G-catalyzed Translocation

Coupled translocation of mRNA and tRNA through the ribosome, a process catalyzed by elongation factor EF-G, is a crucial step in protein synthesis. The crystal structure of a translocation complex describes the binding states of two tRNAs trapped in mid-translocation. The deacylated P-site tRNA has...

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Publicat a:Science
Autors principals: Zhou, Jie, Lancaster, Laura, Donohue, John Paul, Noller, Harry F.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242719/
https://ncbi.nlm.nih.gov/pubmed/25190797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1255030
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